Table 1.

Nomenclature, function, and distribution of heat shock proteins.

Gene symbol	Description	Stress-inducible	Localization∗	Reference
HSPB1	HspB1; Hsp25 (mice); Hsp27 (rats, humans)	+	Brain, retina, spinal cord, sciatic nerve	Dean and Tytell, 2001; Kirbach and Golenhofen, 2011
HSPB2	HspB2; MKBP	-	Brain, sciatic nerve	Kirbach and Golenhofen, 2011
HSPB3	HspB3	-	Brain, spinal cord, sciatic nerve	Kirbach and Golenhofen, 2011
HSPB4	HspB4; αA-crystallin	+	Retina, sciatic nerve	Xi et al., 2003; Kirbach and Golenhofen, 2011; Ruebsam et al., 2018
HSPB5	HspB5; αB-crystallin	+	Brain, retina, spinal cord, sciatic nerve	Bhat and Nagineni, 1989; Xi et al., 2003; Kida et al., 2010; Kirbach and Golenhofen, 2011
HSPB6	HspB6; αC-crystallin	-	Brain, spinal cord, sciatic nerve	Kirbach and Golenhofen, 2011
HSPB7	HspB7	-	Sciatic nerve	Kirbach and Golenhofen, 2011
HSPB8	HspB8; Hsp22; H11 kinase	+	Brain, spinal cord, sciatic nerve	Kirbach and Golenhofen, 2011; Ramirez-Rodriguez et al., 2013
HSPB9	HspB9	Unknown	Testis	Kappé et al., 2001
HSPB10	HspB10	Unknown	Testis	Fontaine et al., 2003
HSPB11	HspB11	-	Brain, spinal cord, sciatic nerve	Kirbach and Golenhofen, 2011
HSPA1A, B	Hsp70 family A, members 1A and 1B	+	Brain, retina, spinal cord	Manzerra and Brown, 1992; Tytell et al., 1994; D’Souza and Brown, 1998; Dean et al., 1999; Loones et al., 2000
HSPA8	Hsc70	-	Brain, retina, spinal cord	D’Souza and Brown, 1998; Dean et al., 1999; Loones et al., 2000; Chen and Brown, 2007
HSP90AA1	Hsp90α family class A, member 1	+	Brain, retina, spinal cord	Ishimoto et al., 1998; Loones et al., 2000; Bernstein et al., 2001; Zuehlke et al., 2015
HSP90B1	Hsp90β family member 1; Gp96; Grp94	-	Brain, retina, spinal cord	Ishimoto et al., 1998; Loones et al., 2000; Bernstein et al., 2001
HSPH1	Hsp105	+	Brain, dorsal root ganglion	Hatayama et al., 1997; Saito et al., 2007

^∗Not an exhaustive list. Special attention was given to the distribution of heat shock proteins in the nervous system.