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. 2018 Nov 20;5:180263. doi: 10.1038/sdata.2018.263

Table 3. Description of data records.

File Name Description Type Location URL
Primary Files
ADMC_ADNI1_LIPIDOMICS.csv Normalized & filtered lipidomics dataset. First column in this file is the RID and rest of the columns are lipid ids. Data LONI http://dx.doi.org/10.7303/syn10208594.1
ADNI_ADMCLIPIDOMICS_DICT.csv Data dictionary for lipid species. It has the ionization mode, adduct information, precursor ion value, retention time and InChiKey values. Data Dict LONI http://dx.doi.org/10.7303/syn10208614.1
ADMC Supplemental Materials
ADNI1_LIPIDOMICS_RAW_DATA_ESI_POS.zip Raw LC-MS data files (ESI + mode) in the Agilent (.d) format. Data LONI http://dx.doi.org/10.7303/syn10495782.1
ADNI1_LIPIDOMICS_RAW_DATA_ESI_NEG.zip Raw LC-MS data files (ESI -mode) in the Agilent (.d) format. Data LONI http://dx.doi.org/10.7303/syn10495771.1
wcmc-lipidomics-database.zip Curated database of plasma lipid ions for ESI ( + /-) modes. It has m/z values, adduct information and retention time for the targets. Metadata Synapse http://dx.doi.org/10.7303/syn10208660.1
adni1-lipidomics-acq.zip Agilent Qual 7.0 method that used for the data acquisition on the LCMS instrument. Method Synapse http://dx.doi.org/10.7303/syn10208671.1
adni1-lipidomics-eics.zip Extracted Ion Chromatograms in .csv format for ESI ( + /-) modes. These files were generated by the Agilent Qual software. Data LONI http://dx.doi.org/10.7303/syn10495758.2
adni1-lipidomics-script.r R-script for data generation and quality control Script Synapse http://dx.doi.org/10.7303/syn10208679.1
adni1_acqtime.zip Details about sample acquisition time and labels. It is required by the R-script Method Synapse http://dx.doi.org/10.7303/syn10208662.1
adni1_qcrsd_ttest.csv RSDs in QC samples and the p-values (student t-test paired) for duplicates samples Data LONI http://dx.doi.org/10.7303/syn10208665.3
adni1_lipidomics_data_processing.zip Input, intermediate and output data matrices used by the R-script. Data Synapse https://www.synapse.org/#!Synapse:syn12973205
adni1_lipidomics_isa_tab.zip ISA-tab file for the RID to raw LCMC data files mapping Data Synapse https://www.synapse.org/#!Synapse:syn12972536
adni1_loess_results.zip PCA plots for before and after the LOESS normalization Data Synapse https://www.synapse.org/#!Synapse:syn12973204
Clinical Data
ADNI_All_Clinical_Data_16May2016.csv Clinical variables (a subset of ADNI’s complete list) snapshot from May, 2016 Data LONI http://dx.doi.org/10.7303/syn7477271.1
Fasting Status.txt Fasting status of participants at time of blood draw Data Synapse http://dx.doi.org/10.7303/syn9774830.1
ADNI Key Clinical Variables Subset Data Dictionary.xlsx Data dictionary for a key subset of variables in ADNI_All_Clinical_Data_16May2016.csv (for full version see “Data Dictionary [ADNI1,GO,2] (DATADIC.csv)” on LONI) Data dict Synapse http://dx.doi.org/10.7303/syn9758900.1