Scheme 3.
Synthesis of fragment 10. Reagents and conditions: a) TBSCl, NaH, THF, rt; b) phthalimide, PPh3, DEAD, THF, 0 °C to rt; c) H2NNH2·H2O, MeOH, reflux; d) BzCl, Et3N, CH2Cl2, 0 °C; e) TBAF, THF, rt.
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