Fig. 2.

Multiparametric ultrasound of a palpable, 20-mm large lesion in the craniolateral right breast of a 23-year-old patient. a In B-mode, the lesion was heterogeneously hypoechoic, lobulated, with a partially indistinct margin and was classified as BI-RADS 4a. b In VTIQ elastography, the lesion was overall quite soft, with a SWVmax of 2.62 m/s. c Power Doppler detected internal vascularity and the spectrum analysis of the most prominent artery demonstrated an RI of 0.64. The application of the classification algorithm would classify this lesion as node 6, with probability of malignancy of 2.7 %, making a follow-up instead of biopsy a safe alternative. Ultrasound guided biopsy revealed an area of sclerosing adenosis