Table 2.

Clinical and dermoscopic features of BCC and keratinocytic lesions and potential therapies

Lesion	Clinical features	Dermoscopic features	Potential therapy
BCC subtypes
Nodular	Nodular	Arborizing telangiectasias, ulceration Ovoid nests, other pigmented structures	Nonsurgical therapy could be considered for thin and small lesions, but PDT should be avoided for pigmented lesions
Superficial	Flat/scaly	Superficial fine telangiectasias, multiple erosions Pigmented structures (but not ovoid nests)	Nonsurgical therapy could be considered, but PDT should be avoided for pigmented lesions
Infiltrative	Plaque (ill-defined borders)	Arborizing vessels (finer and scattered), ulceration Ovoid nests, blue-gray dots	Surgery
Keratinocytic lesion subtypes
AK	Erythematosquamous plaques	Facial AK: ‘strawberry’, granular pattern Nonfacial AK: white scales and erythema	Nonsurgical methods are recommended for facial and nonfacial AKs and can be combined with surgical ablationa for nonfacial AKs
Intraepidermal carcinoma or Bowen’s disease	Erythematosquamous plaques	Unpigmented variant: glomerular vessels + yellowish scales Pigmented variant (up to 6% of cases in the study by Cameron et al. [31]): linear pigmented structures	Nonsurgical methods could be considered, but PDT should be avoided for pigmented lesions
Invasive SCC/keratoacanthoma	Nodular	White circles, white color polymorphic/thrombosed vessels	Surgery

AK actinic keratosis, BCC basal cell carcinoma, PDT photodynamic therapy, SCC squamous cell carcinoma

^aSurgical ablation such as curettage or cryotherapy