Table 3.

Results from linear regression models between independent variables of EDE cargo proteins, plasma cytokines, and neuroimaging, with processing speed as dependent variable.

	GLUT1	LAT1	P-GP	NOSTRIN	VCAM1	IL-6	MCP-1	TNFα	WMH	GM
R2	0.2	0.2	0.3	0.14	−0.05	0.2	0.2	−0.009	−0.006	−0.02
β	0.5	0.46	0.6	0.43	0.07	0.5	0.5	0.2	0.37	0.5
p-Value	0.02∗	0.03∗	0.009∗	0.06	0.7	0.02∗	0.04∗	0.4	0.3	0.3
Prob >F	0.04	0.06	0.019	0.1	0.6	0.04	0.08	0.4	0.4	0.5

Models are adjusted for age and in the case of imaging biomarkers for total intracranial volumes. Distributions were normalized by log transformation. Significant associations are starred.