Table 1.
Baseline characteristics (randomized population)
| Demographic characteristics | Pregabalin (n = 275) | Placebo (n = 267) | Total (N = 542) |
|---|---|---|---|
| Age (years) | |||
| Mean (SD) | 52.8 (12.9) | 53.5 (12.6) | 53.1 (12.8) |
| Range | 20–81 | 20–85 | 20–85 |
| Age, years, no. (%) of patients | |||
| 18–44 | 60 (21.8) | 61 (22.8) | 121 (22.3) |
| 45–64 | 163 (59.3) | 156 (58.4) | 319 (58.9) |
| ≥ 65 | 52 (18.9) | 50 (18.7) | 102 (18.8) |
| Race, no. (%) of patients | |||
| White | 217 (78.9) | 215 (80.5) | 432 (79.7) |
| Black | 47 (17.1) | 46 (17.2) | 93 (17.2) |
| Asian | 7 (2.5) | 3 (1.1) | 10 (1.8) |
| Other | 4 (1.5) | 3 (1.1) | 7 (1.3) |
| Weight (kg) | |||
| Mean (SD) | 85.9 (20.0) | 86.2 (19.0) | 86.1 (19.5) |
| Range | 49.1–193.7 | 45.4–166.0 | 45.4–193.7 |
| Height (cm) | |||
| Mean (SD) | 170.1 (10.1) | 168.6 (9.4) | 169.4 (9.8) |
| Range | 142.2–198·0 | 140.0–198.1 | 140.0–198.1 |
| Trauma type, no. (%) of patients | |||
| Surgical | 131 (47.6) | 138 (51.7) | 269 (49.6) |
| Non-surgical | 144 (52.4) | 129 (48.3) | 273 (50.4) |
| Baseline mean pain (daily NRS) | |||
| Mean (SD) | 6.41 (1.3) | 6.5 (1.3) | |
| Questionnaire: PainDETECT [13] | N = 274 | N = 265 | |
| Mean (SD) | 23.1 (5.52) | 22.6 (5.52) | |
| Range | 2–36 | 3–38 | |
NRS numeric rating scale, SD standard deviation