Fig. 3.

Distribution and intensity of top three ranked potential medulloblastoma classifiers based on receiver operating characteristics (ROC) analysis. a The highest ranked classifier for medulloblastoma, PG(38:5) (m/z 797.5336), displayed homogeneous distribution closely related to regions of dense tumor in all subgroups of medulloblastoma. b The second highest medulloblastoma classifier, PG(36:4) (m/z 771.5169), showed similar distribution to PG(38:5) as it was also present in regions of dense tumor in all medulloblastoma subgroups. c The third highest medulloblastoma classifier, PG(36:3) (m/z 773.5335), was also observed in all sections of medulloblastoma. The spatial distribution of these lipid species in medulloblastoma compared to pineoblastoma suggest their potential value as medulloblastoma biomarkers