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. 2018 Aug 20;140(2):269–279. doi: 10.1007/s11060-018-2978-2

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 5 — Non-classifier ions indicative of histopathology rather than tumor type. The ion images of lipid species not discriminative of tumor type were investigated to determine if their distribution could be of interest to underlying biological similarities between medulloblastoma and pineoblastoma. a PC(34:2) (m/z 758.5702) displayed varying intensity across medulloblastoma and pineoblastoma tissue sections that more closely resembled areas of necrosis and hemorrhage rather than viable tumor. b PG(37:0(OH)) (m/z 809.5894) also displayed distribution in the tissue sections not indicative of viable tumor regions, but more related to potential necrosis, or hemorrhage. c PG(40:4) (m/z 827.5809) was observed in both medulloblastoma and pineoblastoma specimens and its distribution was more closely related to regions of viable tumor