Table 2.
Wound-related study characteristics and outcomes
| NPWT group | Comparator group | p value | |
|---|---|---|---|
| Wound duration, weeksa | 21.1 ± 24.7 | 14.4 ± 14.3 | 0.10 |
| Wound area; cm2 a | 15.7 ± 14.6 | 2.9 ± 4.4 | 0.0000 |
| Wound area reduction after 8 ± 1 days; cm2 a | 1.1 ± 1.7 | 0.3 ± 0.7 | 0.20b |
| Wound area reduction after 8 ± 1 days; %a | 10.2 ± 14.41 | 18.0 ± 15.7 | 0.04b |
| Complete ulcer resolution within 1 year; % (n) | 55.1 (27/49) | 73.7 (14/19) | 0.15 |
| Ulcer recurrences within 1 year after complete ulcer resolution; % (n) | 29.2 (7/24) | 31.3 (5/16) | 0.88 |
| Median follow-up, months, mean SD, median, IQ range | 21.1 ± 9.1 21.1 (IQR: 15.9–28.3) |
23.8 ± 10.4 29.8 (IQR: 15.2–31.7) |
0.26 |
| Large amputations; n | 0 | 1 | 0.11 |
| Deaths; n | 3 | 2 | 0.61 |
aData presented as mean ± SD
bThe p-value for the reduction in wound area after 8 ± 1 days in the NPWT was p = 0.0001, while in the comparator group it was 0.0038