Table 3.
Tissue biomarkers and association with progression-free and overall survival
| Biomarker | Number of samples | Progression-free survival | Overall survival | ||||||
|---|---|---|---|---|---|---|---|---|---|
| p value | Hazard ratio | p value | Hazard ratio | ||||||
| Point | 95% CI | Point | 95% CI | ||||||
| Lower | Upper | Lower | Upper | ||||||
| WT1 H-score | |||||||||
| 0 | 13 | Reference | Reference | ||||||
| > 0 | 8 | 0.26 | 1.74 | 0.67 | 4.54 | 0.85 | 0.91 | 0.36 | 2.29 |
| CEA H-score | |||||||||
| ≤ 125 (median) | 12 | Reference | Reference | ||||||
| >125 (median) | 11 | 0.82 | 0.91 | 0.38 | 2.14 | 0.52 | 0.74 | 0.30 | 1.82 |
| hTERT H-score | |||||||||
| ≤ 100 | 12 | Reference | Reference | ||||||
| >100 | 6 | 0.96 | 0.97 | 0.35 | 2.69 | 0.65 | 1.28 | 0.44 | 3.74 |
| PDL1 total proportion score | |||||||||
| < 50 | 9 | Reference | Reference | ||||||
| ≥ 50 | 7 | 0.51 | 1.43 | 0.5 | 4.14 | 0.40 | 1.68 | 0.50 | 5.62 |