Table 3.

Breast cancer after genetic testing among non-affected BRCA carriers

Carriers without a history of breast cancera	55 cases
Observation period after genetic testing (average)	0–13.9 years (2.5)
Age at genetic testing (average)	Age 20–66 (age 38.6)
Breast cancer onset after genetic testing	4 cases
Incidence rate	4/137.5 (persons/person years) 2.9%/year
BRCA1 positive 2 cases, BRCA2 positive 2 cases
Opportunities for detection	MRI: 2 cases, DCIS MMG: 1 case, DCIS Self-detection: 1 case, invasive 3.2 cm

DCIS ductal carcinoma in situ, MMG mammography, MRI magnetic resonance imaging

^aIncluding one patient with a history of cervical cancer and another with a history of ureter cancer