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. 2018 Sep 17;172(3):587–595. doi: 10.1007/s10549-018-4951-3

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 2 — a Single-projection specimen mammogram revealing a peripherally located IDC + DCIS lesion (orange arrow). b Reconstructed micro-CT slices (1.35 mm apart) similarly depict the peripherally located mass. Notable metal reconstruction artifacts occur because of the localization wire. c Orthogonal micro-CT slices (4.2 mm apart) suggest a close peripheral margin, and also indicate a close deep margin, which would not be evident in the single-projection specimen mammogram. Micro-CT scale bar is 1 cm. d 3D volume rendering of the specimen, with the adipose tissue thresholded to be transparent, revealed a micro-calcification cluster, a large smooth calcification, tumor location metal clip, and calcified vasculature (white arrows) in the presentation (see video in Additional File 3)