Table 3.
Subgroup Cox’s proportional hazard ratio analysis of reoperation for recurrence
| Subgroup | Reoperation rate | LWM | ||
|---|---|---|---|---|
| (n) | (%) | Hazard ratio | P | |
| Age, years | ||||
| < 59 | 195/5971 | 3.3 | 1.70 (1.28–2.27) | < 0.001 |
| ≥ 59 | 272/6177 | 4.4 | 1.40 (1.10–1.78) | 0.006 |
| Type of defect | ||||
| Direct | 215/5510 | 3.9 | 1.75 (1.33–2.29) | < 0.001 |
| Direct in patients < 59 years | 87/2635 | 3.3 | 2.39 (1.56–3.66) | < 0.001 |
| Direct in patients ≥ 59 years | 128/2875 | 4.5 | 1.39 (0.98–1.98) | 0.065 |
| Indirect | 198/5310 | 3.7 | 1.33 (1.01–1.76) | 0.045 |
| Size of defect | ||||
| < 1.5 cm | 72/1981 | 3.6 | 1.32 (0.83–2.11) | 0.245 |
| > 3 cm | 118/2648 | 4.5 | 1.54 (1.07–2.22) | 0.021 |
Values in parentheses are 95% confidence intervals. HWM, reference. Women were excluded in all subgroup analyses. Age is divided by median. Significant P values are in bold face