Table 1.
Participant baseline characteristics and participation and weight loss outcomes in VA-DPP and Online-DPP, comparing those <65 and ≥65 years of age
| Age <65 years (N = 258) |
Age ≥65 years (N = 120) |
P values, overall comparison between age <65 vs. ≥65 | |||||
|---|---|---|---|---|---|---|---|
| Overall | VA-DPP (N = 139) | Online-DPP (N = 119) | Overall | VA-DPP (N = 59) | Online-DPP (N = 61) | ||
| Baseline characteristics | |||||||
| Age, mean (SD) | 54.7 (7.2) | 55.1 (7.0) | 54.4 (7.5) | 70.1 (5.5) | 68.7 (4.8) | 71.4 (5.9) | <0.001 |
| Female, n (%) | 82 (31.8) | 24 (17.3) | 58 (48.7) | 8 (6.7) | 2 (3) | 6 (10) | <0.001 |
| Weight, kg; mean (SD) | 106.2 (21.1) | 111.8 (20.3) | 99.2 (19.9) | 103.4 (18.9) | 106.6 (19.1) | 100.2 (18.2) | 0.23 |
| BMI, kg/m2; mean (SD) | 35.1 (5.6) | 36.2 (5.5) | 33.8 (5.4) | 32.9 (5.6) | 33.6 (5.1) | 32.3 (6.0) | <0.001 |
| Race, n (%) | <0.001 | ||||||
| Black | 92 (35.7) | 64 (46.0) | 28 (23.5) | 21 (17.5) | 16 (27) | 5 (8) | |
| White | 147 (57.0) | 63 (45.3) | 84 (70.6) | 96 (80.0) | 40 (68) | 56 (92) | |
| Other | 11 (4.3) | 4 (2.9) | 7 (5.9) | 1 (0.8) | 1 (2) | 0 (0) | |
| Missing | 8 (3.1) | 8 (5.8) | 0 (0.0) | 2 (1.7) | 2 (3) | 0 (0) | |
| Comorbidities, n (%) | |||||||
| HTN | 160 (62.0) | 90 (64.7) | 70 (58.8) | 90 (75.0) | 44 (75) | 46 (75) | 0.013 |
| CAD | 20 (7.8) | 12 (8.6) | 8 (6.7) | 26 (21.7) | 14 (24) | 12 (20) | <0.001 |
| Mental health | 140 (54.3) | 81 (58.3) | 59 (49.6) | 43 (35.8) | 24 (41) | 19 (31) | <0.001 |
| HbA1c %, mean (SD) | 6.0 (0.2) | 6.0 (0.2) | 6.0 (0.2) | 6.0 (0.2) | 6.0 (0.2) | 6.0 (0.2) | 0.77 |
| Participation outcomes, n (%) | |||||||
| Completed 4+ sessions | 219 (84.9) | 109 (78.4) | 110 (92.4)* | 103 (85.8) | 48 (81) | 55 (90) | 0.81 |
| Completed 8+ sessions | 181 (70.2) | 79 (56.8) | 102 (85.7)* | 91 (75.8) | 37 (63) | 54 (89)* | 0.25 |
| Predicted mean change in weight, kg (95% CI) | |||||||
| 6-month weight loss | −5.79 (−6.65, −4.92) | −5.05 (−6.09, −4.01) | −5.85 (−6.76, −4.95) | −5.91 (−7.02, −4.81) | −5.30 (−6.62, −3.98) | −5.96 (−7.10, −4.81) | 0.81 |
| 12-month weight loss | −5.00 (−5.89, −4.10) | −5.22 (−6.46, −3.98) | −4.98 (−5.92, −4.03) | −5.55 (−6.68, −4.41) | −5.43 (−7.03, −3.82) | −5.55 (−6.73, −4.37) | 0.32 |
| Predicted mean change in weight, % (95% CI) | |||||||
| 6-month weight loss | −5.76 (−6.58, −4.93) | −4.98 (−5.96, −3.99) | −5.83 (−6.70, −4.96) | −5.97 (−7.01, −4.93) | −4.78 (−6.02, −3.54) | −6.05 (−7.12, −4.97) | 0.66 |
| 12-month weight loss | −5.02 (−5.88, −4.17) | −5.17 (−6.35, −3.99) | −5.01 (−5.91, −4.11) | −5.60 (−6.67, −4.53) | −4.95 (−6.47, −3.43) | −5.63 (−6.74, −4.52) | 0.26 |
P values are results from ANOVA for continuous variables and Pearson χ2 test for categorical and binary variables comparing participants <65 years of age to those ≥65 years of age. Pearson χ2 test for pairwise comparisons and proportion test were performed to compare VA-DPP to Online-DPP participants within each age group (*P < 0.05) and to compare participants <65 years of age to those ≥65 years of age within each study (all P > 0.05). CAD, coronary artery disease; HTN, hypertension.