Figure 4.

Inhibition of CETP activity by anacetrapib modified HDL function. A: Anti-inflammatory effect of HDL particles. B: HDL capacity for cellular cholesterol efflux. C: Antioxidative function of HDL particles from each group was assessed as the ability to suppress LDL-oxidation. Significant differences were determined using repeated-measures by both factors two-way ANOVA with Bonferroni multiple comparison test (n ≥ 6 for each group). *P < 0.05, ***P < 0.001, ****P < 0.0001. A₂₃₄, absorbance reading at 234 nm; Ana, anacetrapib.