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Chemically induced colitis elevated serum C-reactive protein (CRP) levels and activation of the hypothalamic-pituitary-adrenal (HPA) axis. The graph displays the effect of dextran sodium sulfate (DSS) on serum CRP levels (A), and the effect of DSS treatment on HPA axis (B–C). (B) Cortisol concentration at 0 day, 3 days, and 7 days after DSS treatment. (C) Corticosterone concentration at 0 day, 3 days, and 7 days after DSS treatment. *Significant difference (p<0.05).
