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Dextran sodium sulfate (DSS)-induced colitis caused cyclooxygenase 2 (COX-2) mRNA changes in different brain regions. Graphs show the effects of DSS-induced colitis in mice on COX-2 mRNA levels (A) in the hippocampus, (B) in the amygdala, and (C) in the hypothalamus after exposure to 3 and 7 days of DSS. The values are expressed as fold changes normalized to the untreated control group. The values represent means±standard error of mean; *p<0.05.
