Table 6.
ORs for XRCC3 rs861539 genotype and childhood ALL after stratification by gender
| Genotype | Males, n | OR (95% CI)a | aOR (95% CI)b | P-valuec | Females, n | OR (95% CI)a | aOR (95% CI)b | P-value | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
| ||||||||||
| Controls | Cases | Controls | Cases | |||||||
|
| ||||||||||
| AA | 135 | 114 | 1.00 (ref) | 1.00 (ref) | 106 | 100 | 1.00 (ref) | 1.00 (ref) | ||
| AG | 9 | 25 | 3.29 | 3.07 | 0.0024* | 10 | 14 | 1.48 | 1.54 | 0.3640 |
| (1.48–7.33) | (1.63–6.59) | (0.63–3.49) | (0.61–3.67) | |||||||
| GG | 4 | 9 | 2.66 | 2.25 | 0.0987 | 2 | 4 | 2.12 | 2.23 | 0.3814 |
| (0.80–8.88) | (0.58–9.47) | (0.38–11.83) | (0.51–13.38) | |||||||
| Ptrend | 0.1492 | 0.0012* | ||||||||
Notes:
a
Multivariate logistic regression analysis;
b
Multivariate logistic regression analysis after adjusted of age;
c
P-value based on chi-squared test.
*
Statistically significant.
Abbreviation: ALL, acute lymphoblastic leukemia.