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. 2018 Nov 15;10:5735–5745. doi: 10.2147/CMAR.S182183

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© 2018 Zhu et al. This work is published and licensed by Dove Medical Press Limited

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Molecular mechanism of ENO1 action in HCC.

Notes: GSEA of the relationship between high ENO1 expression and genes associated with cell cycle (KEGG_cell_cycle) (A), and DNA replication (KEGG_DNA_ replication) (B). The scatter plot of the linear association between ENO1 expression level and MKI67 (C), PCNA (D), CDK4 (E), CDK2 (F), and MELK (G).

Abbreviations: ENO1, enolase-1; ES, enrichment score; FDR, false discovery rate; GSEA, gene set enrichment analysis; HCC, hepatocellular carcinoma; NES, normalized enrichment score; TPM, transcripts per millions.