Table S2.
Results of subgroup analysis of the ENO1 expression in nontumor tissues and HCC samples
| Subgroup analysis | Number of studies | Number of patients | Pooled HR | P-value | Heterogeneity
|
|
|---|---|---|---|---|---|---|
| I2 (%) | P-value (χ2) | |||||
| Region | ||||||
| Asian countries | 4 | 623 | 1.06 (0.89–1.23) | <0.001 | 0.0 | 0.486 |
| Western countries | 8 | 2,751 | 0.83 (0.74–0.92) | <0.001 | 86.1 | <0.001 |
| Sample size | ||||||
| ≤100 | 5 | 356 | 0.83 (0.59–1.07) | <0.001 | 76.1 | 0.002 |
| >100 | 7 | 2,395 | 0.89 (0.80–0.97) | <0.001 | 85.5 | <0.001 |
Abbreviations: ENO1, enolase-1; HCC, hepatocellular carcinoma.