Table 1.
1,4-Addition of benzylamine to α,β-unsaturated esters.
Entry | Product | Power (Watts) | T (oC) | Pressure (psi) | Time (min) | Yield (%) |
---|---|---|---|---|---|---|
1 | (±)-3a | 37 | 150 | 110 | 180 | 98 |
2 | (±)-3a | 55 | 140 | a | 180 | 83 |
3 | (±)-3b | 50 | 115-130 | 68 | 180 | 97 |
4 | (±)-3b | 55 | 140 | a | 390 | 80 |
5 | 3c:6 | 50 | 115 | 59 | 180 | 50:50b |
6 | 3c:6 | 50 | 65 | 5 | 10 | 70:30b |
7 | 3c:6 | 40 | 65 | c | 10 | 70:30b |
8 | 3c:6 | 40 | 65 | c | 3 | 90:10b |
anot determined.
bRatio between reaction products 3c and 6 (see description results)
cReaction was performed in an open system.