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. 2008 Nov 3;13(11):2740–2749. doi: 10.3390/molecules13112740

Table 1.

Sensitivity of human pathogenic microbes to the new synthetic heterocyclic compounds using the hole method.

Compound Conc. (g/mL) Pathogens
Aa B C D E
Tobramycin 0.010 15b 13 22 - 14
0.005 13 11 17 - 8
2a 0.010 11 12 12 - 9
0.005 8 10 8 - -
2b 0.010 13 13 14 - 8
0.005 8 8 9 - -
2c 0.010 - 8 11 - -
0.005 - - 8 - -
2d 0.010 - 9 10 - 8
0.005 - - 8 - -
3a 0.010 8 12 10 8 14
0.005 - 9 8 - 10
3b 0.010 9 11 11 - 15
0.005 - 10 8 - 12
3c 0.010 8 8 10 8 14
0.005 - - 9 - 10
3d 0.010 - - 8 - 8
0.005 - - - - -
3e 0.010 13 13 19 10 15
0.005 13 - 14 9 9

a A: Staphylococcus aureus; B: Escherichia coli; C: Candida albicans; D: local resistant Pseudomonas aeruginosa; E: reference Pseudomonas aeruginosa ATCC 27853.

b Inhibition zone diameter measured in mm.