Table 5.

Inhibition of protein interaction in AN assay by compounds 3a-3w (concentration: 50 µM, standard deviation ≤ 6 %).

	n = 5		n = 4		n = 3
R	compound	inhibition (%)	compound	inhibition (%)	compound	inhibition (%)
H	3a	4	3i	1	3q	5
Methyl	3b	8	3j	5	3r	4
Ethyl	3c	13	3k	4	3s	4
n-Propyl	3d	32	3l	53	3t	23
iso-Propyl	3e	9	3m	4	3u	11
n-Butyl	3f	49	3n	49	3v	64
iso-Butyl	3g	69	3o	67	3w	42
tert-Butyl	3h	58	3p	44	terfenadine	27