Table 6.
Sleep Quantity and Quality Measures in Relation to Hippocampal Volume for Cognitively Normal Subjects compared to Subjects with CIND/Dementia
| Normal | CIND/Dementia | |||||
|---|---|---|---|---|---|---|
| Sleep Measure | Estimateb | Std. Error | p value | Estimateb | Std. Error | p value |
| Sleep quantity a | ||||||
| Short (<7 hours) | 5.604e-6 | 1.130e-4 | 0.96 | −3.826e-5 | 2.260e-4 | 0.87 |
| Long (>8 hours) | −5.300e-5 | 1.170e-4 | 0.65 | 2.424e-5 | 1.620e-4 | 0.88 |
| Sleep somnolence | −4.116e-6 | 3.146e-6 | 0.20 | 5.869e-6 | 3.581e-6 | 0.12 |
| Sleep problems index II | −3.458e-6 | 4.939e-6 | 0.49 | 7.653–6 | 5.543e-6 | 0.18 |
| Sleep adequacy | −2.120e-7 | 4.851e-6 | 0.96 | −9.182e-6 | 6.814e-6 | 0.19 |
Abbreviations: CIND, cognitive impairment no dementia
a
Participants in the short sleep (<7 hours) and long sleep (>8 hours) categories are compared to participants in the optimal sleep group (7–8 hours).
b
Every unit increase in the sleep measure is associated with an increase or decrease (−) in units of hippocampal volume.
Note: Hippocampal volume was adjusted for intracranial volume.