Table 1.
Microscopic evaluation scheme of healing burn wounds
Grade 0 | Grade 1 | Grade 2 | Grade 3 | Grade 4 | |
---|---|---|---|---|---|
Inflammation | |||||
Neutrophils* | Mild | Moderate | Marked | Severe | |
Eosinophils* | Mild | Moderate | Marked | Severe | |
Lymphocytes & plasma cells | 0 to 5 Organized Units | 6 to 10 | 11 to 15 | 16 to 20 | >21 |
Histiocytes/MNGC†/mineral | <10% | 10 to 25% | up to 50% | up to 75% | >80% |
Dermal Response | |||||
Blood/edema | <10% | 10 to 25% | up to 50% | up to 75% | >80% |
Necrosis, stromal | <10% | 10 to 25% | up to 50% | up to 75% | >80% |
Granulation tissue | <10% | 10 to 25% | up to 50% | up to 75% | >80% |
Characterized by fibroblasts and increased density of small caliber capillaries | |||||
Mature dermis | <10% | 10 to 25% | up to 50% | up to 75% | >80% |
Characterized by mature, dense collagen and fibrocytes | |||||
Dermal wound bed | Measure Length | ||||
Epithelial Response | |||||
Epithelial proliferation | >3× or healed wound | 2.5× | 2× | 1.5× | ≤Normal thickness |
Epithelial gap | <40% Open | Up to 40% | Up to 60% | Up to 80% | >100% |
Details provided in Table 2.
Multinucleated giant cells.