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. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: Trends Biotechnol. 2018 Sep 10;36(12):1244–1258. doi: 10.1016/j.tibtech.2018.07.004

Figure 2.

Figure 2

Key Figure 

Protein and Peptide Discovery and Engineering for Gas Sensing

For a Figure360 author presentation of Figure 2, see the figure legend at https://doi.org/10.1016/j.tibtech.2018.07.004.

For a Figure360 author presentation of Figure 2, see the figure legend at https://doi.org/10.1016/j.tibtech.2018.07.004.

(A) Superimposition of the binding pockets of bovine and porcine odorant-binding proteins (OBPs) reveals how small differences in residue composition lead to different volatile organic compound (VOC) affinities [51]. (B) The extraction of volatile binding sequence from the fruit fly OBP LUSH, as a way to rationally develop peptides for VOC detection [62,63]. (C) Phage-display panning screens a multitude of peptide sequences against a graphitic surface mimicking benzene [68]. (D) Computational techniques predict the best peptide–VOC pairs to be experimentally tested [70].