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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Am J Gastroenterol. 2017 Nov 7;113(3):317–321. doi: 10.1038/ajg.2017.409

Figure 4:

Figure 4:

Deep submucosal invasion, identified by central depression, loss of surface and vascular patterns, and a non-lifting sign. These are the major visible predictors of deep invasion and unresectability.