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. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: Ann Surg Oncol. 2018 Oct 11;25(13):4037–4046. doi: 10.1245/s10434-018-6859-x

Figure 2.

Figure 2.

Overall and disease-free survival analyses with multivariate Cox model and Kaplan Meier curve for the three-miRNA signature in TCGA dataset. A, the patients with high score of the three miRNAs signature (n=52) have significantly poor prognosis than the patients with low score (n=999) for overall survival (p=0.0004), as well as for disease-free survival (p<0.0001). Validation analyses for survival using three independent data sets; METABRIC cohort (C), GSE19536 (D); GSE22220 (E) showed that the three miRNAs signature have a significant impact on patient survival in the three independent cohorts derived from cBioPortal and GEO dataset.