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. Author manuscript; available in PMC: 2019 Nov 15.
Published in final edited form as: Int J Radiat Oncol Biol Phys. 2018 Jun 13;102(4):821–829. doi: 10.1016/j.ijrobp.2018.06.003

Figure 5: Correlation of habitat risk score (HRS) maps with histopathology.

Figure 5:

(a) Pseudowhole mount H&E-stained histopathology sections. The consecutive axial slices are displayed from apex (left) to base (right). Tumor nodules are labeled with the corresponding Gleason Score (GS). The right posterior nodule displays heterogeneity with GS increasing from 3+4=7, to 4+3=7, and then to 4+4=8 (apex to base). The GS of the right anterior tumor nodule changes from 3+3=6 to 3+4=7 and back to 3+3=6; (b) Corresponding HRS maps, displayed on axial T2w slices. Image data was resampled at the same spacing (0.3 to 0.4 cm) as the histopathology specimens. The red color intensities of the heat-map are associated with the higher microscopic GS.

Abbreviations: A = anterior; L = left; P = posterior; R = right