Table 1.
Particle concentration in IVIG solution after 48 hours of agitation and subsequent centrifugation
| Particles 60-1000 nm (108/mL) | Particles ≥ 1 μm (#/mL) | |
|---|---|---|
| Agitation for 48 hours | n/aa | 918,000 ± 260,000 |
| Centrifugation 45 minutes, 2350 g | 10.04 ± 7.0 | 1,900 ± 2000 |
| Centrifugation 45 minutes, 30000 g | 0.47 ± 0.14 | 1,300 ± 1,400 |
| Centrifugation 3 hours, 112,000 g | 0.07 ± 1.27 | 140 ± 80 |
*
Measurement error represents standard deviation from measurement of three independent samples
a
Samples above the limit of detection of the instrument (ca 109 particles/mL)