Table 1.

A summary of the complexity levels of the four synthetic data sets

	Set 1	Set 2	Set 3	Set 4
Mutation types	SNV, structural variation (SV) (deletions, duplications, inversions)	SNV, SV (deletions, duplications, insertions, inversions)	SNV, SV (deletions, duplications, insertions, inversions) & INDEL	SNV, SV (deletions, duplications, inversions) & INDEL
Number of Somatic SNVs	3535	4322	7903	16,268
Cellularity	100%	80%	100%	80%
Subclone variant allele frequencies (VAFs)	N/A	N/A	50%, 33%, 20%	50%, 35% (effectively 30% and 15% due to cellularity)