Appendix 1—table 3. Perturbing the cis-acting step in the sequential activation model.

Parameter	Description
$k_f^0=k_C(1-d)$	cis-activation rate, from non-expressing to mono-allelic state
$k_f^1=k_C(1-f\cdot d)$	cis-activation rate, from mono-allelic to bi-allelic state
$k_r^0=k_C\cdot d$	back cis-activation rate, from mono-allelic to non-expressing state
$k_r^1=k_C\cdot f\cdot d$	back cis-activation rate, from bi-allelic to mono-allelic state
$k_T$	trans-activation rate
$d$	0 to 0.35
$f$	0.4