Table 3.

QoL measures and domains

Instrument	QoL domains	Study
SF-12 (12 items) [39]	Physical functioning Role physical Bodily pain General health Mental health Role emotional Social functioning Vitality	[8]
SF-6D (6 items) [42]	Physical functioning Role limitations Pain Mental health Social functioning Vitality	[38]
EQ-5D (5 items and a VAS on current overall health) [43]	Mobility Self-care Usual activities Pain/discomfort Anxiety/depression	[30, 33, 37]
Personal Well-being Index (PWI) (8 items and a single question of satisfaction with life as a whole) [45]	Standard of living Personal health Achieving in life Personal relationships Personal safety Community connectedness Future security Spirituality/religion	[33, 37]
WHOQOL-BREF (27 items) [18]	Physical Psychological Social relationships Environment	[29]
Quality of Life Questionnaire (QLQ) (192 items) [46]	Material well-being Physical well-being Personal growth Marital relations Parent/child relations Extended family relations Extramarital relations Altruistic behavior	[36]
Wolcott & Glezer’s well-being scale (12 items) [48]	Standard of living Relationship Personal feelings of self-worth	[35]
A single question on overall QoL: How satisfied are you with your life?	Open-ended questions about the seriousness of the impact of their close relative’s drinking or substance misuse on their health and well-being	[34]