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. 2018 Nov 19;49:114. doi: 10.1186/s13567-018-0610-2

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Interaction networks of the identified differentially abundant proteins and known putative virulence factors. Protein–protein interactions of differentially abundant proteins with a confidence score ≥ 0.4 are shown. Green nodes represent known putative virulence factors collected from published literature, and orange nodes represent differentially abundant proteins in M. hyopneumoniae strain 168 compared with strain 168L. Grey lines represent interactions between two nodes.