. Author manuscript; available in PMC: 2018 Nov 20.

Published in final edited form as: Nat Rev Cardiol. 2015 Sep 1;13(1):48–60. doi: 10.1038/nrcardio.2015.124

Table 1 |.

Clinically available tests for HDL function and dysfunction^131,132

Test	Population	Disease association
Macrophage cholesterol efflux	Patients with stable CHD (case-control)	CAD⁸¹
Monocyte chemotaxis assay	Patients with stable CHD (case-control)	CAD¹⁶
Cell-free assay	Patients with stable CHD (case-control)	CAD¹⁶
*Proteomics*
Oxidized tryptophan	Patients with stable CHD or ACS (case-control)	CVD⁶
Chlorinated tyrosine-192	Patients with stable CHD or ACS (case-control)	CAD¹³
Oxidized methionine-148	Patients with stable CHD or ACS (case-control)	CAD¹³
Apolipoprotein C-III on HDL	Prospective population	CVD events⁵⁰

Abbreviations: ACS, acute coronary syndrome; CAD, coronary artery disease; CHD, coronary heart disease; CVD, cardiovascular disease; HDL, high-density lipoprotein.