Table 3.
Comparison of clinical prediction scores for severe ADAMTS13 deficiency
| PLASMIC score | French score, points | Bentley score, points | ||
|---|---|---|---|---|
| Component of score | ||||
| Platelet count | <30 × 109/L: 1 point | ≤30 × 109/L: 1 point | >35 × 109/L:−30 points | |
| Creatinine level | <2 mg/dL: 1 point | ≤2.26 mg/dL: 1 point | >2 mg/dL:−11.5 points | |
| Parameters of hemolysis | Reticulocyte count >2.5%: 1 point | — | Reticulocyte: >3% +21 points | |
| Indirect bilirubin >1.5 mg/dL:+20.5 points | ||||
| Haptoglobin undetectable: 1 point | ||||
| Indirect bilirubin >2 mg/dL: 1 point | ||||
| Associated conditions | No active cancer: 1 point | — | — | |
| No history of solid-organ or hematopoietic stem cell transplant: 1 point | ||||
| MCV | <90 fL: 1 point | — | — | |
| INR | <1.5: 1 point | — | — | |
| ANA | — | Positive: 1 point | — | |
| d-dimer | — | — | >4 mcg/mL:−10 points | |
| Interpretation | ||||
| Risk category, total score | ||||
| Low | 0-4 | 0 | <20 | |
| Intermediate | 5 | 1 | 20-30 | |
| High | 6-7 | 2-3 | >30 | |