Table 2.
SNP rs9289231 Genotype prevalence and allele frequency in the case and control individuals*
|
KALRN
Genotypes/Alleles |
Normal Coronary Subjects (n=244) |
Early-Onset CAD Patients (n=268) |
Odd Ratio | 95% CI | P |
|---|---|---|---|---|---|
| TT | 158 (64.7) | 133 (49.6) | Reference | ||
| GT | 73 (30.0) | 83 (30.9) | 1.35 | 0.91–1.99 | 0.131 |
| GG | 13 (5.3) | 52 (19.5) | 4.13 | 2.48–9.10 | <0.001 |
| T allele | 389 (79) | 349 (65) | Reference | ||
| G allele | 99 (21) | 187 (35) | 2.11 | 1.27–2.59 | 0.001 |
SNP, Single nucleotide polymorphism; CAD, Coronary artery disease; GG, Homozygous carrier of a G allele; GT, Heterozygous carrier of G and T alleles; TT, Homozygous carrier of a T allele
*
Data are presented as n (%)