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. 2018 Nov 21;7:185. doi: 10.1038/s41426-018-0186-y

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — Three-day-old BALB/c mice were i.p. inoculated with CV-B5/JS417 (3.16 × 10³ CCID₅₀/mouse). To exclude the impact of the viral load in the serum, the viral load ratio (tissue/serum) was calculated by dividing the mean viral load of each tissue with the viral load of the serum at 6, 12, 24, 72, 120, and 168 h post-challenge (n = 3, per time point)