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. 2018 Nov 21;7:187. doi: 10.1038/s41426-018-0191-1

Fig. 5. P12-34 protects mice against lethal DENV challenge.

Fig. 5

Stat1−/− mice subcutaneously challenged with a lethal dose of DENV-2 were intraperitoneally treated with P12-34 (2.5 mg/kg per day) or vehicle control (DMSO) for the first 6 days of infection. a Survival of mice with or without P12-34 treatment. The P value was determined using a Log-rank (Mantel-Cox) test (n = 5). b The viral loads in sera quantified by RT-qPCR are shown as the mean (bar) and as individual data. *p < 0.05, determined by two-tailed Student’s t-test (n = 5)