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. 2018 Nov 14;12:847. doi: 10.3389/fnins.2018.00847

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Copyright © 2018 Kim, He, Phan, Ahmed, Rye, Piguet, Hodges and Halliday.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Increased risk for cardiovascular disease (CVD) in bvFTD. (A) The apoB:apoA-I ratio was significantly increased in bvFTD; a ratio value greater than 1.0 (red line) is regarded as increased CVD risk. (B) The apoB:apoA-II ratio was significantly increased in bvFTD. (C) The apoA-I:apoA-II ratio was unchanged in bvFTD and AD. (D) The triglyceride:HDL-cholesterol ratio was significantly increased in bvFTD; a ratio value greater than 0.87 (red line) is regarded as increased CVD risk. (E) The total cholesterol:HDL-cholesterol ratio was significantly increased in bvFTD; a ratio value greater than 5.0 (red line) is regarded as increased CVD risk. Bars represent mean and SE, ^∗p < 0.05. (F) ApoA-I levels correlated positively with HDL-cholesterol levels.