Table 2.
Gene expression in cultured macaque follicles.
| Gene | Controla | VD3 |
|---|---|---|
| Preantral follicle | ||
| AMHR2b | 1.3 ± 0.2 | 1.3 ± 0.2 |
| FSHR | 1.9 ± 0.4 | 3.0 ± 0.8 |
| BMP15 | 3.5 ± 0.9 | 7.2 ± 2.7 |
| GDF9 | 2.9 ± 0.7 | 4.6 ± 1.3 |
| Antral follicle | ||
| AMHR2 | 0.9 ± 0.1 | 0.8 ± 0.1 |
| LHCGR | 2.8 ± 0.8 | 4.0 ± 0.9 |
| CYP17A1 | 0.7 ± 0.3 | 0.9 ± 0.5 |
| CYP19A1 | 7.6 ± 1.5 | 11.3 ± 2.6 |
aData represent 4 pooled samples from 8 animals, with follicles from 2 animals per sample, in each experimental group. Values represent the relative expression of the target gene versus the expression of invariant mitochondrial ribosomal protein S10, and are the mean ± SEM with each sample as an individual data point. bVD3, 1α,25-dihydroxyvitamin D3 supplementation; AMHR2, anti-Müllerian hormone receptor II; BMP15, bone morphogenetic protein 15; CYP17A1, cytochrome P450 family 17 subfamily A polypeptide 1; CYP19A1, cytochrome P450 family 19 subfamily A polypeptide 1; FSHR, FSH receptor; GDF9, growth differentiation factor 9; LHCGR, luteinizing hormone/choriogonadotropin receptor.