Table 1.

Variants detected in the 84-years old woman affected by familial CCM.

Gene	Variant
KRIT1	rs17164451 c.485+65G>C
	rs2027950 c.989+63C>G
	rs11542682 c.1980A>G p.Val660 = (HGMD MUT CM105502)
CCM2	rs2304689 c.205-36A>G
	rs11552377 (HGMD CM105503) c.358G>A p.Val120Ile
	rs55967204 c.745+98G>C
	rs2289367 c.915G>A p.Thr305 =
	rs2289369 c.915+119C>T
	IVS10-1G>A