Skip to main content
. 2018 Nov 21;38(6):BSR20180876. doi: 10.1042/BSR20180876

Figure 1. Light microscopy of renal tissue of rats in group Con (Con), group CI-AKI (CI-AKI), group Rap1 (Rap1), and group Rap2 (Rap2).

Figure 1

Descriptions of the groups are in the text. Intraperitoneal injection of large dose of contrast media induced severe renal tubular degeneration and necrosis (group CI-AKI). Rapamycin markedly and dose-dependently attenuated contrast media-induced renal tubular degeneration and necrosis (group Rap1 and Rap2). Arrows indicate tubular necrosis and cell denudation (Hematoxylin-and-Eosin stain; magnification: ×200). Each group (n=6).