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. 2018 Nov 21;38(6):BSR20180876. doi: 10.1042/BSR20180876

Figure 2. Changes in autophagy- and mitophagy-related protein expression following contrast exposure with or without rapamycin.

Figure 2

(A) The expression of LC3, P62, Beclin-1, and Pink1 protein was measured by Western blot analysis in kidneys from rats in group Con (Con), group CI-AKI (CI-AKI), group Rap1 (Rap1), and group Rap2 (Rap2). Descriptions of the groups are in the text. Contrast exposure induced autophagy in TEC cells. Rapamycin significantly up-regulated the expression of LC3-II/I, Beclin-1 and down-regulated the expression of P62. (B) Data show the mean ± S.D. Experiments were repeated three times. *P<0.05 compared with Con; #P<0.05 compared with CI-AKI; &P<0.05 compared with Rap1.