Table 2. Biochemical measurements of liver functions for normal control, artemisinin administrated mice, LCA, and LCA + artemisinin co-treated mice.
| Group | Parameter | |||||
|---|---|---|---|---|---|---|
| AST (U/l) | ALT (U/l) | ALP (U/l) | TBIL (mg/dl) | DBIL (mg/dl) | Amylase (U/l) | |
| Control | 170 ± 1.62 | 49 ± 1.22 | 89 ± 1.06 | 0.03 ± 0.01 | 0.02 ± 0.02 | 3149 ± 131 |
| Artemisinin | 290 ± 43 | 58 ± 4.2 | 63 ± 8.8 | 0.18 ± 0.03 | 0.12 ± 0.04 | 2556 ± 177 |
| Lithocholic A | 5718 ± 367† | 1665 ± 33.2† | 61 ± 6.6 | 0.93 ± 0.03† | 0.57 ± 0.04† | 1853 ± 59† |
| LCA + artemisinin | 179 ± 4.1* | 42 ± 1.7* | 63 ± 3.81 | 0.08 ± 0.02* | 0.12 ± 0.03* | 3160 ± 95* |
Values are represented by mean ± SEM for triplicates experiments. †Represents P values of LCA-treated mice corresponding to normal control. *Represents P values of LCA + artemisinin co-treated mice corresponding to LCA-treated mice.