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. 2018 Nov 21;38(6):BSR20180620. doi: 10.1042/BSR20180620

Figure 4. ANRIL regulated ABCC1 and ABCC5 positively in CRC cell lines.

Figure 4

(A and B) The expression of ABCC1 and ABCC5 was decreased by knockdown of ANRIL in HCT116 and SW480 cells. (C and D) The expression of ANRIL was up-regulated by overexpression of plasmid. (E and F) The expression of ANRIL was increasing in HCT116 and SW480 cells transfected overexpressing plasmid. Error bars indicate the means ± SD of three independent experiments; *P<0.05; **P<0.01; ***P<0.001. (G and H) The expression of ABCC1 was significantly increased in rectum cancer (G) and colon adenocarcinoma (H) from TCGA samples. (I and J) The expression of ABCC5 was not significant difference in rectum cancer (I) and colon adenocarcinoma (J) from TCGA samples.