. Author manuscript; available in PMC: 2019 Dec 1.

Published in final edited form as: SLAS Discov. 2018 Jul 10;23(10):1070–1082. doi: 10.1177/2472555218787140

Table 1.

Statistical summary of screening campaigns.

Statistic	Pilot	ChemBridge (CB) EXPRESS-Pick	Maybridge (MB) HitDis-cover
No. of Compounds	4,400	55,230	52,160
Mean (+) Control ± SD (AU)	1.00 ± 0.01	0.98 ± 0.03	0.94 ± 0.04
Mean (−) Control ± SD (AU)	0.438 ± 0.004	0.28 ± 0.01	0.28 ± 0.01
Mean R (AU) ± SD	0.56 ± 0.01	0.70 ± 0.03	0.66 ± 0.04
Mean Z′ ± SD	0.6 ± 0.1	0.7 ± 0.1	0.7 ± 0.1
No. of Hits (%)	14 (0.318%)	36 (0.065%)	101 (0.194%)
No. Replicated & Active^* (%)	5 (0.114%)	16 (0.029%)	12 (0.023%)

>20% inhibition at 20 μM