A. Low magnification photomicrograph shows DOR-ir in the CA3 region of the dorsal hippocampus; box indicates area of CA3b sampled for densitometry and EM studies. DG = dentate gyrus. B. Representative high magnification photomicrographs of stratum oriens (SO), pyramidal cell layer (PCL), stratum lucidum (SLu), and stratum radiatum (SR) of CA3b from a Sal-female (Sal F),and a Sal-male (Sal M). C. Sal-females compared to Sal-males show significantly greater DOR-ir levels in stratum oriens and stratum lucidum of CA3b. Scale bars: A = 100 µm **p < 0.01, *p < 0.05; N = 6 rats per group).