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IL-2/IL-2Ab poststroke treatment reduces ischemic brain injury and improves sensorimotor functions after tMCAO. C57BL/6 mice were posttreated with IL-2/IL-2Ab complex or IsoAb intraperitoneally for 3 d starting from 2 h after tMCAO. A, Infarct volume was measured by MAP2 immunostaining 7 d after tMCAO. n = 9–10/group. Scale bar, 1 mm. B, Sensorimotor functions were accessed by rotarod test and foot fault test after stroke. n = 6–9/group. *p < 0.05, **p < 0.01, ***p < 0.001.
